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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIN28B
All Species:
31.82
Human Site:
Y130
Identified Species:
58.33
UniProt:
Q6ZN17
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6ZN17
NP_001004317.1
250
27084
Y130
K
P
K
G
D
R
C
Y
N
C
G
G
L
D
H
Chimpanzee
Pan troglodytes
XP_001143220
250
27053
Y130
K
P
K
G
D
R
C
Y
N
C
G
G
L
D
H
Rhesus Macaque
Macaca mulatta
XP_001086990
248
26863
Y130
K
P
K
G
D
R
C
Y
N
C
G
G
L
D
H
Dog
Lupus familis
XP_539064
251
27158
Y129
K
P
K
G
D
R
C
Y
N
C
G
G
L
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q45KJ6
247
26884
Y128
K
P
K
G
D
R
C
Y
N
C
G
G
L
D
H
Rat
Rattus norvegicus
P62961
322
35711
R154
P
R
R
R
G
P
P
R
N
Y
Q
Q
N
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506004
274
29355
Y150
K
P
K
G
D
R
C
Y
N
C
G
G
L
D
H
Chicken
Gallus gallus
Q45KJ4
250
27379
Y130
K
P
K
G
D
R
C
Y
N
C
G
G
L
D
H
Frog
Xenopus laevis
Q8AVK2
252
27965
Y133
K
P
K
G
D
R
C
Y
N
C
G
G
L
D
H
Zebra Danio
Brachydanio rerio
Q803L0
202
21867
A86
R
S
L
K
E
G
E
A
V
E
F
T
F
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRN5
195
21575
G80
M
S
G
F
R
S
L
G
E
Q
E
E
V
E
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492281
196
21765
R81
E
R
S
N
G
K
G
R
E
A
Y
A
V
S
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38896
201
19059
V86
S
G
P
D
G
A
P
V
Q
G
N
S
G
G
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98
88.4
N.A.
85.5
24.5
N.A.
73.3
82.8
77.3
52.7
N.A.
31.6
N.A.
27.2
N.A.
Protein Similarity:
100
99.5
98
91.6
N.A.
90
36.9
N.A.
78.4
88.4
85.7
62.7
N.A.
44.4
N.A.
39.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
100
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
100
100
13.3
N.A.
13.3
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
33.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
8
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
62
0
0
62
0
0
0
0
0
% C
% Asp:
0
0
0
8
62
0
0
0
0
0
0
0
0
62
0
% D
% Glu:
8
0
0
0
8
0
8
0
16
8
8
8
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
8
0
8
0
8
% F
% Gly:
0
8
8
62
24
8
8
8
0
8
62
62
8
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
62
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
62
0
62
8
0
8
0
0
0
0
0
0
0
8
0
% K
% Leu:
0
0
8
0
0
0
8
0
0
0
0
0
62
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
70
0
8
0
8
0
0
% N
% Pro:
8
62
8
0
0
8
16
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
8
8
8
0
0
8
% Q
% Arg:
8
16
8
8
8
62
0
16
0
0
0
0
0
0
8
% R
% Ser:
8
16
8
0
0
8
0
0
0
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
62
0
8
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _